Commentary: Lifestyle factors and colorectal cancer microsatellite instability--molecular pathological epidemiology science, based on unique tumour principle

Source: http://ije.oxfordjournals.org/cgi/content/short/41/4/1072?rss=1

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Amyloid “spells” trouble

Publication year: 2012
Source:The Lancet, Volume 380, Issue 9853

Andreas Charidimou, Ruth Law, David J Werring

Source: http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=IRSSSEARCH&_method=citationSearch&_piikey=S0140673612613336&_version=1&md5=0dbb65af338c9e427bd05a0bee855455

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Effects of physical inactivity on non-communicable diseases – Authors' reply

Publication year: 2012
Source:The Lancet, Volume 380, Issue 9853

I-Min Lee, Steven N Blair, Peter T Katzmarzyk

Source: http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=IRSSSEARCH&_method=citationSearch&_piikey=S014067361261873X&_version=1&md5=32eed35efd72ef2b4008816727b5840f

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Osteoprotegerin is associated with hip fracture incidence: the Tromso Study

Background Osteoprotegerin (OPG) is a cytokine essential for the regulation of bone resorption, but large longitudinal studies on its relationship to fracture risk in humans are lacking. In this population-based study of 2740 men and 2857 post-menopausal women, it was examined whether serum OPG was associated with hip fracture incidence. The participants were followed for 15 years.

Methods Baseline measurements included height, weight and serum OPG, and information about lifestyle, prevalent diseases and use of medication.

Results Men with OPG in the highest quartile were 2.79-fold [95% confidence interval (CI) 1.34–5.82] more likely to have a hip fracture during follow-up, compared with those with OPG in the lowest quartile (P-trend over OPG quartiles ≤0.001, after adjustments for age and other confounders). In women not using post-menopausal hormone therapy (HT), the risk of hip fracture was 1.64-fold higher (95% CI 0.94–2.86) in the highest quartile compared with the lowest OPG quartile (P-trend over OPG quartiles = 0.05). No relationship was found in post-menopausal women using HT (P-trend over OPG quartiles = 0.23).

Conclusions In men, OPG was positively associated with the incidence of hip fracture. In post-menopausal women not using HT a similar, but weaker, relationship was found.

Source: http://ije.oxfordjournals.org/cgi/content/short/41/4/1033?rss=1

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Cohort Profile: The international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa

Source: http://ije.oxfordjournals.org/cgi/content/short/41/5/1256?rss=1

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Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care

New England Journal of Medicine, Volume 0, Issue 0, Ahead of Print.

Source: http://www.nejm.org/doi/full/10.1056/NEJMoa1209759?ai=rv&af=R&rss=currentIssue

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Positive risk taking: Whose risk is it? An exploration in community outreach teams in adult mental health and learning disability services.

Health, Risk & Society; 04/01/2011
(AN 59702712)
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